OncoMatch/Clinical Trials/NCT06241755
Clinical Trial for Evaluating the Efficacy and Safety of BCG for Therapeutic Use in the Prevention of Postoperative Recurrence of Medium/High-risk Non-muscle Invasive Bladder Cancer (NMIBC)
Is NCT06241755 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including BCG for Therapeutic Use and BCG for Therapeutic Use for non-muscle invasive bladder cancer.
Treatment: BCG for Therapeutic Use · BCG for Therapeutic Use — A phase III multi-center randomized, double-blind and positive-controlled clinical trial for evaluating the efficacy and safety of BCG for Therapeutic Use（BCG） in the prevention of postoperative recurrence of medium/high-risk non-muscle invasive bladder cancer (NMIBC).
Check if I qualifyExtracted eligibility criteria
Cancer type
Urothelial Carcinoma
Disease stage
Required: Stage TIS
Excluded: Stage MUSCLE INVASIVE, FOCAL ADVANCED, METASTATIC MUSCULAR INFILTRATION
Grade: G3 (advanced grade) tumor, except for simple in situ tumor
medium/high-risk non-muscle invasive urothelial bladder cancer (T1/Ta/Tis)
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Must have received: transurethral resection of bladder tumor (TURBt)
After a thorough TURBt, all tumors should be grossly invisible. Patients requiring a second procedure are also eligible for inclusion.
Cannot have received: BCG bladder instillation
A previous history of never receiving any therapy of BCG bladder instillation
Lab requirements
Blood counts
ANC ≥1500/mm3 or ≥1.5×10^9/L; platelet ≥100000/mm3 or 100×10^9/L; hemoglobin ≥9 g/dL
Kidney function
estimated creatinine clearance ≥50 mL/min according to the formula of Cockcroft-Gault
Liver function
total serum bilirubin ≤1.5× ULN; for subjects with Gilbert syndrome total serum bilirubin <3×ULN; AST/ALT ≤2.5×ULN
Clinical laboratory tests fulfilling the following features: ... see above
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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