OncoMatch/Clinical Trials/NCT06241612

Individualized Elective Neck Irradiation in NPC Patients

Is NCT06241612 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for nasopharyngeal carcinoma.

Phase 3RecruitingSun Yat-sen UniversityNCT06241612Data as of May 2026

To evaluate whether individualized elective neck irradiation for nasopharyngeal carcinoma based on the vertebral level of metastatic lymph nodes can reduce the incidence of radiation-related adverse effects and improve patients' quality of life，without reducing survival.

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage T1-4N0-2, N3 CATEGORY OF NON-BILATERAL LOWER-NECK NODE METASTASIS

staged as T1-4N0-2 or N3 category of non-bilateral lower-neck node metastasis

Prior therapy

No prior treatment (treatment-naive required)

Max 0 prior lines

Cannot have received: chemotherapy

previous chemotherapy treatment

Cannot have received: surgery

Exception: except diagnostic

surgery (except diagnostic) to the neck or nasopharyngeal regions

Cannot have received: radiation therapy

radiotherapy to the neck or nasopharyngeal regions

Lab requirements

Blood counts

leucocyte count > 4 × 10^9/L, haemoglobin > 90 g/L, and a thrombocyte count > 100×10^9/L

adequate haematological function, with a leucocyte count > 4 × 10^9/L, haemoglobin > 90 g/L, and a thrombocyte count > 100×10^9/L

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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