OncoMatch

OncoMatch/Clinical Trials/NCT06241612

Individualized Elective Neck Irradiation in NPC Patients

Is NCT06241612 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies non-drug interventions for nasopharyngeal carcinoma.

Phase 3RecruitingSun Yat-sen UniversityNCT06241612Data as of Jun 2026Location: China

To evaluate whether individualized elective neck irradiation for nasopharyngeal carcinoma based on the vertebral level of metastatic lymph nodes can reduce the incidence of radiation-related adverse effects and improve patients' quality of life,without reducing survival.

Check if I qualify

Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage T1-4N0-2, N3 CATEGORY OF NON-BILATERAL LOWER-NECK NODE METASTASIS

staged as T1-4N0-2 or N3 category of non-bilateral lower-neck node metastasis

Demographics

Ages ≤ 70

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: chemotherapy

previous chemotherapy treatment

Cannot have received: surgery

Exception: except diagnostic

surgery (except diagnostic) to the neck or nasopharyngeal regions

Cannot have received: radiation therapy

radiotherapy to the neck or nasopharyngeal regions

Lab requirements

Blood counts

leucocyte count > 4 × 10^9/L, haemoglobin > 90 g/L, and a thrombocyte count > 100×10^9/L

adequate haematological function, with a leucocyte count > 4 × 10^9/L, haemoglobin > 90 g/L, and a thrombocyte count > 100×10^9/L

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06241612 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

What disease stage is eligible?

Stage T1-4N0-2 or N3 CATEGORY OF NON-BILATERAL LOWER-NECK NODE METASTASIS is required.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify