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OncoMatch/Clinical Trials/NCT06239194

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

Is NCT06239194 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies MDX2001 for biliary tract cancer.

Phase 1/2RecruitingModeX Therapeutics, An OPKO Health CompanyNCT06239194Data as of May 2026

Treatment: MDX2001This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.

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Extracted eligibility criteria

Cancer type

Cholangiocarcinoma

Breast Carcinoma

Cervical Cancer

Colorectal Cancer

Endometrial Cancer

Esophageal Carcinoma

Gastric Cancer

Head and Neck Squamous Cell Carcinoma

Hepatocellular Carcinoma

Non-Small Cell Lung Carcinoma

Pancreatic Cancer

Prostate Cancer

Renal Cell Carcinoma

Thyroid Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Lab requirements

Blood counts

adequate hematologic function

Kidney function

adequate renal function

Liver function

adequate hepatic function

Adequate hematologic, hepatic and renal function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Sarah Cannon Research Institute · Denver, Colorado
  • Sylvester Comprehensive Cancer Center - University of Miami Health System · Miami, Florida
  • Massachusetts General Hospital · Boston, Massachusetts
  • Sarah Cannon Research Institute · Nashville, Tennessee
  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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