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OncoMatch/Clinical Trials/NCT06228079

Adjuvant vs Surgery Only in Early-stage Recurrent NPC

Is NCT06228079 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including Immunotherapy,Toripalimab and Chemotherapy,Gemcitabine based regimen for recurrent nasopharyngeal carcinoma.

Phase 3RecruitingEye & ENT Hospital of Fudan UniversityNCT06228079Data as of Jun 2026Location: China

Treatment: Immunotherapy,Toripalimab · Chemotherapy,Gemcitabine based regimenAdjuvant Therapy Versus Endoscopic Surgery Alone in Early-stage Recurrent Nasopharyngeal Carcinoma: A Multicenter Randomized Controlled Trial

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Chemotherapy,Gemcitabine based regimen

Other

Immunotherapy,Toripalimab

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage RT1, RT2, RT3

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≤ 75

Prior therapy

Must have received: radiation therapy

previously radiotherapy for only 1 course

Must have received: surgery

Undergone endoscopic surgery with negative pathological margin

Cannot have received: radioactive particle planting

History of radioactive particle planting

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06228079 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radioactive particle planting disqualifies patients from enrollment.

What disease stage is eligible?

Stage RT1 or RT2 or RT3 is required.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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