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OncoMatch/Clinical Trials/NCT06223646

A Study of KQ-2003 CAR-T Cell Therapy for Patients With Relapsed or Refractory Multiple Myeloma

Is NCT06223646 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies KQ-2003 CAR T-cells for multiple myeloma.

Phase 1/2RecruitingNovatim Immune Therapeutics (Zhejiang) Co., Ltd.NCT06223646Data as of May 2026

Treatment: KQ-2003 CAR T-cellsThis is a multicenter, open-label, dose-escalation/expansion phase 1/2a study to evaluate the safety, tolerability, pharmacokinetic/pharmacodynamic characteristics and determine the recommended dose of KQ-2003 CAR T-cells for patients with Relapsed/Refractory Multiple Myeloma

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: BCMA-CD19 dual-target CAR-T cell therapy

Subjects who had previously received BCMA-CD19 dual-target CAR-T cell products or autologous stem cell transplantation within 12 weeks before the collection of peripheral blood mononuclear cells

Cannot have received: autologous stem cell transplantation

Exception: within 12 weeks before the collection of peripheral blood mononuclear cells

Subjects who had previously received BCMA-CD19 dual-target CAR-T cell products or autologous stem cell transplantation within 12 weeks before the collection of peripheral blood mononuclear cells

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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