OncoMatch

OncoMatch/Clinical Trials/NCT06208150

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Is NCT06208150 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments for multiple myeloma.

Phase 3RecruitingJanssen Research & Development, LLCNCT06208150Data as of May 2026

Treatment: Talquetamab · Pomalidomide · Teclistamab · Elotuzumab · Dexamethasone · BortezomibThe purpose of this study is to compare the effectiveness of either talquetamab plus pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd).

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: anti-CD38 antibody

Participants...who have received an anti-CD38 antibody

Must have received: immunomodulatory agent (lenalidomide)

Participants...who have received...lenalidomide

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • UCSF Fresno · Clovis, California
  • UCLA · Santa Monica, California
  • Yale University School Of Medicine · New Haven, Connecticut
  • Medical Oncology Hematology Consultants, PA · Newark, Delaware
  • Memorial Healthcare System · Hollywood, Florida

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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