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OncoMatch/Clinical Trials/NCT06207305

A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma

Is NCT06207305 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including Dexamethasone and Famotidine for metastatic appendiceal adenocarcinoma.

Phase 1/2RecruitingM.D. Anderson Cancer CenterNCT06207305Data as of Jun 2026

Treatment: Dexamethasone · Diphenhydramine · Famotidine · PaclitaxelTo find the recommended dose of the drug paclitaxel that can be given intraperitoneally (given directly into the abdominal cavity) to participants with metastatic appendiceal adenocarcinoma.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Paclitaxel

Other

DexamethasoneDiphenhydramineFamotidine

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Blood counts

leukocytes ≥3000/mcl, absolute neutrophil count ≥1,500/mcl, platelets ≥75,000/mcl

Kidney function

creatinine ≤ 1.5x institutional uln

Liver function

total bilirubin ≤ institutional upper limit of normal (uln)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06207305 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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