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OncoMatch/Clinical Trials/NCT06190782

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Is NCT06190782 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including PD-1 inhibitor+/- chemotherapy combined with local therapy and systemic therapy alone for esophageal squamous cell carcinoma.

Phase 3RecruitingFudan UniversityNCT06190782Data as of May 2026

Treatment: PD-1 inhibitor+/- chemotherapy combined with local therapy · systemic therapy alonePatients with oligometastatic squamous cell carcinoma were enrolled and randomly assigned to receive either PD-1 inhibitor +/- chemotherapy combined with local therapy or PD-1 inhibitor +/- chemotherapy alone. The primary end point was progression-free survival (PFS). The secondary end points included overall survival, side effects and local control.

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Extracted eligibility criteria

Cancer type

Esophageal Carcinoma

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: pd-1 inhibitor

Exception: progression disease after pd-1 inhibitor treatment

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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