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OncoMatch/Clinical Trials/NCT06176027

Azacytidine Plus CAOLD Regimen in Relapsed/Refractory Peripheral T-Cell Lymphomas

Is NCT06176027 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies Azacytidine plus CAOLD regimen for relapsed peripheral t-cell lymphomas.

Phase 1/2RecruitingNavy General Hospital, BeijingNCT06176027Data as of May 2026

Treatment: Azacytidine plus CAOLD regimenThis is a multicenter prospective single arm phase II study. The purpose of this study is to evaluate the safety and efficiency of azacytidine combined with CAOLD Regimen in the treatment of relapsed/refractory peripheral t-cell lymphomas.

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Extracted eligibility criteria

Prior therapy

Min 1 prior line

Lab requirements

Blood counts

ANC ≥ 1.5 x 10^9/L (≥ 1 x 10^9/L if bone marrow involvement by lymphoma); Platelet ≥ 75 x 10^9/L (≥ 50 x 10^9/L if BM involvement by lymphoma); Hemoglobin ≥ 8 g/dL

Meet the following lab criteria: Absolute Neutrophil Count (ANC) ≥ 1,5 x 10^9/L (≥ 1 x 10^9/L if bone marrow (BM) involvement by lymphoma); Platelet ≥ 75 x 10^9/L (≥ 50 x 10^9/L if BM involvement by lymphoma); Hemoglobin ≥ 8 g/dL.

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