OncoMatch/Clinical Trials/NCT06173401
Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases
Is NCT06173401 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for spinal metastases.
The goal of this study is to determine whether fractionated Stereotactic radiosurgery (SRS) for spine metastases is associated with improved local tumor control compared to single-fraction SRS. Patients will be randomized to treatment with spine SRS using either 22 Gy in 1 fraction or 28 Gy in 2 fractions.
Check if I qualifyExtracted eligibility criteria
Disease stage
Metastatic disease required
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: radiation therapy
Prior or planned radiation off study within or overlapping with study treatment site
Cannot have received: surgery
Prior surgery to spinal site intended to be treated with protocol SRS
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Stanford University School of Medicine · Palo Alto, California
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