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OncoMatch/Clinical Trials/NCT06170710

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

Is NCT06170710 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Anti-PD-1 monoclonal antibody for head and neck squamous cell carcinoma.

Phase 2RecruitingCancer Institute and Hospital, Chinese Academy of Medical SciencesNCT06170710Data as of Jun 2026Location: China

Treatment: Anti-PD-1 monoclonal antibodyThis trial aims to evaluate whether the addition of anti-PD-1 antibody to adjuvant postoperative chemoradiotherapy could improve disease free survival in patients with high-risk locally advanced head and neck squamous cell carcinoma (HNSCC).

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Extracted eligibility criteria

Treatments studied

Other

Anti-PD-1 monoclonal antibody

Cancer type

Head and Neck Squamous Cell Carcinoma

Biomarker criteria

Required: PD-L1 (CD274) cps > 1 (cps > 1)

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 70

Prior therapy

Cannot have received: anti-pd-1/pd-l1 therapy

Lab requirements

Blood counts

Adequate organ function

Kidney function

Adequate organ function

Liver function

Adequate organ function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06170710 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior anti-pd-1/pd-l1 therapy disqualifies patients from enrollment.

Does this trial require CD274?

Yes, CD274 cps > 1 is a required biomarker for enrollment.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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