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OncoMatch/Clinical Trials/NCT06168487

Telmisartan in Prostate Cancer

Is NCT06168487 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies Telmisartan for prostate cancer.

Phase 1RecruitingTyler J CurielNCT06168487Data as of May 2026

Treatment: TelmisartanThe goal of this clinical trial is to learn about the tolerability of telmisartan in patients with prostate cancer, but evidence for treatment efficacy will also be gathered.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: standard of care agent for prostate cancer (cabazitaxel, docetaxel, abiraterone, olaparib, rucaparib, talazoparib plus enzalutamide) — receiving or likely to receive

Participants must be receiving or likely to receive one of the following SOC agents for PC: cabazitaxel, docetaxel (alone or plus abiraterone) olaparib, rucaparib, or talazoparib plus enzalutamide

Cannot have received: angiotensin I receptor blocker

Angiotensin l receptor blocker use currently or within the 30 days prior to day 1, cycle 1.

Cannot have received: (lithium)

Patients on lithium therapy in any form

Cannot have received: (rituximab)

Patients who received rituximab ... within 30 days prior to first telmisartan dose on this study

Cannot have received: (amifostine)

Patients who received ... amifostine within 30 days prior to first telmisartan dose on this study

Cannot have received: (ramapril)

Patients on ramapril

Lab requirements

Blood counts

hb >10 gm/dl

Kidney function

serum creatinine ≤2.5 or estimated gfr >30 cc/min

Liver function

scot ≤3x uln

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Dartmouth Health · Lebanon, New Hampshire

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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