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OncoMatch/Clinical Trials/NCT06144736

PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND

Is NCT06144736 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin for seminoma.

Phase 2RecruitingHeinrich-Heine University, DuesseldorfNCT06144736Data as of May 2026

Treatment: Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycinPRIMETEST II is an interventional study involving low-volume metastatic seminoma. It explores a novel approach using robot-assisted primary retroperitoneal lymph node dissection, aiming to reduce long-term side effects and improve quality of life. By identifying factors predicting cancer recurrence, the study hopes to tailor treatments for better outcomes. The approach could potentially spare patients from chemotherapy induced long-term side effects while maintaining excellent survival rates, presenting a promising shift in testicular cancer care for this specific patient group.

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Extracted eligibility criteria

Cancer type

Testicular Germ Cell Tumor

Disease stage

Required: Stage IIA, IIB

Excluded: Stage IIC, III

Metastatic disease required

Prior therapy

Must have received: carboplatin (carboplatin) — adjuvant

Recurrence of a CS I tumor after adjuvant therapy with carboplatin mono

Cannot have received: chemotherapy other than carboplatin mono

The patient received a different chemotherapy than described above

Cannot have received: retroperitoneal radiotherapy

The patient underwent retroperitoneal radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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