OncoMatch

OncoMatch/Clinical Trials/NCT06132711

Safety and Efficacy of APRIL-BAFF-Bicephali CAR-T in Relapsed, Refractory Multiple Myeloma

Is NCT06132711 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies non-drug interventions for multiple myeloma.

Phase 1/2RecruitingXuzhou Medical UniversityNCT06132711Data as of Jun 2026Location: China

This is a Single-center, open, single-arm clinical study, the goal of which was to evaluate the safety and efficacy of APRIL-BAFF-Bicephali CAR-T in relapsed and refractory multiple myeloma.The study consisted of four processes: patient enrollment screening; pre-CAR T cell therapy (including leukocyte apheresis, CAR T cell preparation and chemotherapy); inpatient monitoring phase for CAR T cell transfusion; and long-term follow-up phase

Check if I qualify

Extracted eligibility criteria

Cancer type

Multiple Myeloma

Demographics

Ages ≤ 70

Lab requirements

Liver function

ALT and AST <3 times normal; bilirubin <2.0mg / dl

Cardiac function

The patient has no serious heart, liver, kidney and other diseases

ALT and AST <3 times normal; bilirubin <2.0mg / dl; The patient has no serious heart, liver, kidney and other diseases

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06132711 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 70 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify