OncoMatch

OncoMatch/Clinical Trials/NCT06129747

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast

Is NCT06129747 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for breast cancer.

Phase 2RecruitingCase Comprehensive Cancer CenterNCT06129747Data as of May 2026

The standard treatment for participants whose cancer has returned after breast conserving surgery is radiation given twice daily (separated by at least 6 hours) for a total of 30 treatments. The purpose of this study is to find out if giving radiation once a day for 15 treatments after repeat breast conserving surgery works as well as giving it the standard way.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Biomarker criteria

Excluded: BRCA1 mutation

Excluded: BRCA2 mutation

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: radiation therapy — whole breast irradiation

Three years of time must have elapsed since the end of the last course of whole breast irradiation

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center · Cleveland, Ohio
  • Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center · Cleveland, Ohio

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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