OncoMatch/Clinical Trials/NCT06107686
A Study of YL202 in Selected Patients With Advanced Solid Tumors
Is NCT06107686 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies YL202 should be intravenously infused for nsclc.
Treatment: YL202 should be intravenously infused — This study is a multicenter, open-label, phase II study of YL202 in China to evaluate the efficacy, safety, and PK characteristics of YL202 in the following selected patients with advanced solid tumors.
Check if I qualifyExtracted eligibility criteria
Cancer type
Non-Small Cell Lung Carcinoma
Breast Carcinoma
Head and Neck Squamous Cell Carcinoma
Tumor Agnostic
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Cannot have received: HER3-targeted therapy
prior drug therapy targeting HER3 (including antibodies, antibody-drug conjugates [ADCs])
Cannot have received: CAR-T cell therapy
chimeric antigen receptor T-cell immunotherapy (CAR-T)
Cannot have received: topoisomerase I inhibitor
Previously intolerant to topoisomerase I inhibitors or ADC therapy composed of topoisomerase I inhibitors
Cannot have received: antibody-drug conjugate
Previously intolerant to topoisomerase I inhibitors or ADC therapy composed of topoisomerase I inhibitors
Cannot have received: allogeneic bone marrow transplantation
Prior treatment with allogeneic bone marrow transplantation
Cannot have received: solid organ transplantation
Prior treatment with ... solid organ transplantation
Lab requirements
Blood counts
The function of organs and bone marrow meets the requirements within 7 days before the first dose.
Kidney function
The function of organs and bone marrow meets the requirements within 7 days before the first dose.
Liver function
The function of organs and bone marrow meets the requirements within 7 days before the first dose.
The function of organs and bone marrow meets the requirements within 7 days before the first dose.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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