OncoMatch/Clinical Trials/NCT06104553
A Trial of SHR-A1912 Combined With Other Therapies in B-cell Non-Hodgkin 's Lymphoma
Is NCT06104553 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including SHR-A1912; R-Chemo and SHR-A1912; R-Chemo for b-cell non-hodgkin's lymphoma.
Treatment: SHR-A1912; R-Chemo · SHR-A1912; R-Chemo — This study aims to evaluate the safety, PK and preliminary anti-tumour activity of SHR-A1912 combined with other therapies in patients with B-cell non-Hodgkin 's lymphoma.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Non-Hodgkin Lymphoma
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: systemic anti-tumor therapy — relapsed/refractory cohort: at least one (≥ 1) line of prior systemic therapy
Relapsed and/or refractory disease after at least one (≥ 1) line of prior systemic therapy (relapsed/refractory cohort)
Cannot have received: autologous stem cell transplant
Exception: allowed if >12 weeks before first study treatment
Received autologous stem cell transplantation within 12 weeks before the first study treatment
Cannot have received: allogeneic stem cell transplant
previously received allogeneic stem cell transplantation
Cannot have received: CAR-T cell therapy
Exception: allowed if >12 weeks before first study treatment
received Car-T cell therapy within 12 weeks before the first study treatment
Cannot have received: anti-tumour treatment
Exception: allowed if >2 weeks before first study treatment
Received anti-tumour treatment within 2 weeks before the first study treatment
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06104553 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior autologous stem cell transplant, allogeneic stem cell transplant, CAR-T cell therapy disqualifies patients from enrollment.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages