OncoMatch/Clinical Trials/NCT06093438
Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer
Is NCT06093438 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies Toripalimab for cervical cancer.
Treatment: Toripalimab — To explore the efficacy of incorporating neoadjuvant immunotherapy into neoadjuvant chemotherapy in locally advanced cervical cancer patients with high risk of recurrence.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Immunotherapy
Cancer type
Cervical Cancer
Disease stage
Required: Stage IIIB, IIIC, IVA
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Prior therapy
Cannot have received: any prior treatment
Patients received any form of treatment before enrollment
Lab requirements
Blood counts
Hemoglobin ≥ 9.0 g/dl; Neutrophils ≥ 2000 cells/μl; Leukocytes ≥ 4 × 10^9/L; Platelets ≤ 100 × 10^9/L
Kidney function
Serum urea nitrogen (BUN) ≤ 1.5 × upper normal limit (UNL); Serum creatinine (Cr) ≤ 1.5 × upper normal limit (UNL)
Liver function
Serum ALT/AST ≤ 2.5×UNL; Serum Total bilirubin ≤ 1.5× UNL
Cardiac function
No obvious arrhythmia, myocardial ischemia, severe atrioventricular block, cardiac insufficiency or severe heart valve disease
Adequate hematological, renal and hepatic functions: ... Impaired hematological, renal or hepatic functions: Hemoglobin < 9.0 g/dl, Neutrophils < 2000 cells/μl; Leukocytes < 4 × 10^9/L; Platelets > 100 × 10^9/L; Serum ALT/AST > 2.5×UNL; Serum Total bilirubin > 1.5× UNL; Serum urea nitrogen (BUN) > 1.5 × upper normal limit (UNL); Serum creatinine (Cr) > 1.5 × upper normal limit (UNL)
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06093438 currently recruiting?
Yes, this trial is currently recruiting patients.
Can patients have received prior systemic therapy?
No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.
What disease stage is eligible?
Stage IIIB or IIIC or IVA is required.
Is there an age limit?
Yes. Patients must be 75 years or younger.
Is this trial open to male patients?
No. This trial enrolls female patients only.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages