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OncoMatch/Clinical Trials/NCT06092892

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Is NCT06092892 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for breast cancer.

Phase 2RecruitingAlice ChungNCT06092892Data as of May 2026

The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or mastectomy with TAD followed by adjuvant therapy. This is a prospective, single arm phase II clinical trial. Patients will be screened and enrolled per eligibility criteria. Patient, tumor, and treatment data will be documented.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Biomarker criteria

Required: ESR1 overexpression (ER+)

ER+ invasive breast cancer

Excluded: HER2 (ERBB2) overexpression

Her2+ invasive breast cancer [excluded]

Excluded: ESR1 loss

ER- invasive breast cancer [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute · Los Angeles, California
  • CS Cancer at Huntington Cancer Center · Pasadena, California
  • CS Cancer at Valley Oncology Medical Group · Tarzana, California

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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