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OncoMatch/Clinical Trials/NCT06084806

Test-retest Evaluation of [18F]F-AraG PET

Is NCT06084806 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies [18F]F-ARAG PET for non-small cell lung cancer.

Phase 2RecruitingCellSight Technologies, Inc.NCT06084806Data as of May 2026

Treatment: [18F]F-ARAG PETThis pilot study aims to evaluate the test-retest variability of \[18F\]F-AraG-PET imaging in patients with advanced NSCLC tumors. The main objectives of the study are to quantify the uptake of \[18F\]F-AraG in tumors and lymphoid tissue in two consecutive scans spaced not longer than 7 days apart from each other to estimate the magnitude of physiologic and measurement variability. To explore these objectives, eligible subjects will undergo two \[18F\]F-AraG PET/CT scans within 7 days of each other prior to receiving treatment. This study is a single-site, open-label, non-randomized, single-arm pilot trial. Patients and care providers will not be blinded to any part of the study.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Disease stage

Metastatic disease required

candidate to receive immunotherapy as monotherapy or as combination therapy for advanced/metastatic disease

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Iowa Hospitals and Clinics · Iowa City, Iowa

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