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OncoMatch/Clinical Trials/NCT06063486

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

Is NCT06063486 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for clonal cytopenia of undetermined significance.

Phase 2RecruitingUniversity of Southern CaliforniaNCT06063486Data as of May 2026

This phase II trial evaluates how a curcumin supplement (C3 complex/Bioperine) changes the inflammatory response and symptomatology in patients with clonal cytopenia of undetermined significance (CCUS), low risk myelodysplastic syndrome (LR-MDS), and myeloproliferative neoplasms (MPN). Chronic inflammation drives disease development and contributes to symptoms experienced by patients with CCUS, LR-MDS, and MPN. Curcumin has been shown to have anti-inflammatory and anti-cancer properties and has been studied in various chronic illnesses and hematologic diseases.

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Extracted eligibility criteria

Cancer type

Myeloproliferative Neoplasm

Myelodysplastic Syndrome

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Los Angeles General Medical Center · Los Angeles, California
  • USC / Norris Comprehensive Cancer Center · Los Angeles, California

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