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OncoMatch/Clinical Trials/NCT06059469

PSMA-PET/CT to Assess the Expression of Specific Membrane Antigen (PSMA) in Patients With Progressive Triple-negative Breast Cancer.

Is NCT06059469 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for tnbc - triple-negative breast cancer.

Phase 2RecruitingJules Bordet InstituteNCT06059469Data as of May 2026

This is a descriptive, prospective, single centre study. This study will assess PSMA expression via the uptake of radiolabelled PSMA-ligand using PET/CT imaging in mTNBC lesions pre-identified on 18F-FDG PET/CT in order to evaluate the feasibility of molecular radionuclide therapy in refractory mTNBC using the Lutetium-177 radiolabelled PSMA.

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Extracted eligibility criteria

Cancer type

Triple-Negative Breast Cancer

Breast Carcinoma

Biomarker criteria

Required: FOLH1 imaging-defined expression

PSMA-PET/CT to assess the expression of specific membrane antigen (PSMA)

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: investigational agent

Treatment by another molecule that is the object of investigation within 30 days

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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