OncoMatch/Clinical Trials/NCT06059261
Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC.
Is NCT06059261 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Envafolimab and recombinant human endostatin combined with chemoradiotherapy for nasopharyngeal carcinoma.
Treatment: Envafolimab and recombinant human endostatin combined with chemoradiotherapy — This is a single-center, prospective, single-arm, phase II clinical study, to evaluate the therapeutic efficacy and safety of envafolimab combined with chemoradiotherapy and recombinant human endostatin in patients with locally advanced nasopharyngeal carcinoma.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Head and Neck Squamous Cell Carcinoma
Disease stage
Required: Stage III, IVA
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Prior therapy
Cannot have received: radiotherapy
Cannot have received: systemic chemotherapy
Cannot have received: immune checkpoint inhibitor
Lab requirements
Blood counts
WBC ≥ 4000/μL, neutrophils ≥ 2.000/μL, hemoglobin ≥ 9 g/dL, platelets ≥ 100,000/μL
Kidney function
serum creatinine < 1.5 × ULN
Liver function
ALT, AST < 1.5 times the upper limit of normal (ULN), total bilirubin < 1.5 × ULN
Hematology: WBC ≥ 4000/μL, neutrophils ≥ 2.000/μL, hemoglobin ≥ 9 g/dL, platelets ≥ 100,000/μL; Liver function: ALT, AST < 1.5 times the upper limit of normal (ULN), total bilirubin < 1.5 × ULN; Renal function: serum creatinine < 1.5 × ULN
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT06059261 currently recruiting?
Yes, this trial is currently recruiting patients.
Can patients have received prior systemic therapy?
No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.
What disease stage is eligible?
Stage III or IVA is required.
Is there an age limit?
Yes. Patients must be 65 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages