OncoMatch

OncoMatch/Clinical Trials/NCT06056752

QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Is NCT06056752 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies multiple treatments including QH103 Cell and Fludarabine for b-cell acute lymphoblastic leukemia.

Phase 1RecruitingAnhui Provincial HospitalNCT06056752Data as of Jun 2026Location: China

Treatment: QH103 Cell · Fludarabine · CyclophosphamideThis is a single-arm, single-center, interventional, dose-escalation clinical study designed to evaluate the safety and tolerability of QH103 Cell Injection in the treatment of patients with relapsed/refractory B-cell acute lymphoblastic leukemia.

Check if I qualify

Extracted eligibility criteria

Treatments studied

Chemotherapy

FludarabineCyclophosphamide

Other

QH103 Cell

Cancer type

Acute Lymphoblastic Leukemia

Biomarker criteria

Required: CD19 positive

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≥ 14

Prior therapy

Cannot have received: immune cell therapy

Cannot have received: donor lymphocyte infusion

Lab requirements

Kidney function

serum creatinine≤1.5 × upper limit of normal range (uln)

Liver function

glutamine aminotransferase, aspartate aminotransferase ≤3 times uln, total bilirubin ≤1.5 times uln

Cardiac function

left ventricular ejection fraction ≥50% on echocardiography

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06056752 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior immune cell therapy, donor lymphocyte infusion disqualifies patients from enrollment.

Does this trial require CD19?

Yes, CD19 positive is a required biomarker for enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify