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OncoMatch/Clinical Trials/NCT06051240

Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy

Is NCT06051240 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Lithium for cognitive impairment.

Phase 2RecruitingRegion StockholmNCT06051240Data as of Jun 2026Location: Sweden

Treatment: LithiumRandomized, placebo-controlled, double-blinded, parallel group clinical trial to investigate if 6 months of oral lithium tablets (S-lithium 0,5-1,0 mmol/l) will prevent cognitive decline after brain radiotherapy in pediatric brain tumor survivors. Primary outcome measure is Processing Speed Index (PSI) 2 years after start of study treatment.

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Extracted eligibility criteria

Treatments studied

Other

Lithium

Cancer type

Glioblastoma

Demographics

Ages 5–17

Prior therapy

Must have received: radiation therapy — cranial/craniospinal

Lab requirements

Kidney function

cystatin c derived glomerular filtration rate >= 60

Cardiac function

no cardiac failure or heart disease, including brugada syndrome (or family history thereof)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT06051240 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received radiation therapy.

Is there an age limit?

Yes. Patients must be 17 years or younger and at least 5 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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Related pages

Glioblastoma trials