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OncoMatch/Clinical Trials/NCT06049290

A Phase I/II Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

Is NCT06049290 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies LBL-034 for for relapsed/refractory multiple myeloma.

Phase 1/2RecruitingNanjing Leads Biolabs Co.,LtdNCT06049290Data as of May 2026

Treatment: LBL-034 forThis is a single-arm, open-label, multicenter, dose-escalation, and dose-expansion phase I/II clinical study to evaluate the safety, tolerability, pharmacokinetics, immunogenicity, and efficacy of LBL-034 in patients with Relapsed/Refractory Multiple Myeloma (R/R MM).

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: immunomodulatory drug (thymosin, interleukin-2, interferon)

Use of immunomodulatory drugs within 14 days prior to the initial use of the investigational drug, including but not limited to thymosin, interleukin-2, and interferon

Cannot have received: systemic corticosteroid or other immunosuppressant

Exception: topical, ocular, intra-articular, intranasal, and inhaled corticosteroids; short-term use of glucocorticoids for preventive therapy (e.g., to prevent contrast allergy)

Systemic use of corticosteroids or other immunosuppressants within 14 days prior to the initial use of the investigational drug; The following conditions are excluded: Treatment with topical, ocular, intra-articular, intranasal, and inhaled corticosteroids; short-term use of glucocorticoids for preventive therapy (e.g., to prevent contrast allergy)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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