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OncoMatch/Clinical Trials/NCT06043323

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Is NCT06043323 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Axicabtagene Ciloleucel and Cyclophosphamide for follicular lymphoma.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT06043323Data as of Jun 2026

Treatment: Axicabtagene Ciloleucel · Cyclophosphamide · Fludarabine phosphate · Prednisone · Diphenhydramine · AcetaminophenTo learn about the safety of a drug called axicabtagene ciloleucel given in combination with radiation therapy to patients with relapsed/refractory FL.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Axicabtagene Ciloleucel

Chemotherapy

CyclophosphamideFludarabine phosphate

Other

PrednisoneDiphenhydramineAcetaminophen

Cancer type

Non-Hodgkin Lymphoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 2 prior lines

Lab requirements

Blood counts

hemoglobin level ≥ 8 g/dl

Kidney function

crcl ≥ 45 ml/min/m2

Liver function

alt/ast ≤ 2.5 × uln or ≤ 5 x uln if documented liver involvement

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT06043323 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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