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OncoMatch/Clinical Trials/NCT06043323

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Is NCT06043323 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Axicabtagene Ciloleucel and Cyclophosphamide for follicular lymphoma.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT06043323Data as of May 2026

Treatment: Axicabtagene Ciloleucel · Cyclophosphamide · Fludarabine phosphate · Prednisone · Diphenhydramine · AcetaminophenTo learn about the safety of a drug called axicabtagene ciloleucel given in combination with radiation therapy to patients with relapsed/refractory FL.

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 2 prior lines

Lab requirements

Blood counts

hemoglobin level ≥ 8 g/dl

Kidney function

crcl ≥ 45 ml/min/m2

Liver function

alt/ast ≤ 2.5 × uln or ≤ 5 x uln if documented liver involvement

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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