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OncoMatch/Clinical Trials/NCT06036745

Exploratory Single-arm, Single-center Adjuvant Treatment of Stage IIIB-IIIC Gastric Cancer With Combination of Palizumab and SOX Regimen

Is NCT06036745 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Pembrolizumab + SOX for gastric cancer stage iiib-iiic.

Phase 2RecruitingShanghai Minimally Invasive Surgery CenterNCT06036745Data as of May 2026

Treatment: Pembrolizumab + SOXit is an an Exploratory Single-Arm, Single-Center Study of Pembrolizumab in Combination with SOX Regimen for Adjuvant Treatment of Stage IIIB-IIIC Gastric Cancer

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Extracted eligibility criteria

Cancer type

Gastric Cancer

Biomarker criteria

Required: MSI high-frequency microsatellite instability

Consistent with high-frequency microsatellite instability MSI-H

Required: PD-L1 (CD274) high expression (CPS score ≥5)

High expression of PD-L1 (CPS score ≥5)

Disease stage

Required: Stage IIIB, IIIC

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: surgery — adjuvant

after radical resection

Cannot have received: anti-tumor immunotherapy

Have not received anti-tumor immunotherapy

Lab requirements

Blood counts

hemoglobin ≥90g/l; absolute neutrophil count ≥1.5×109/ l; platelet count ≥100×109/ l

Liver function

aspartate or alanine aminotransferase ≤ 2.5 times the upper limit; alkaline phosphatase ≤ 2.5 times the upper normal limit

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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