OncoMatch/Clinical Trials/NCT06030440
De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck
Is NCT06030440 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies non-drug interventions for squamous cell carcinoma of the oral cavity.
This randomized, prospective, multicenter phase II/III trial will study the reduction of radiation volume by eliminating radiotherapy (RT) to the elective neck using strictly defined surgical and radio-oncological standards to reduce radiotherapy-related long-term side effects without affecting locoregional control.
Check if I qualifyExtracted eligibility criteria
Disease stage
Excluded: Stage PT1/2PN0
except glottis cancer (pT1/2pN0)
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Must have received: surgery — primary tumor and neck dissection
Surgery of primary tumor and neck dissection performed according to predefined surgical standard
Cannot have received: radiotherapy
prior radiotherapy in the head and neck region
Cannot have received: chemotherapy
prior chemo- or immunotherapy (neoadjuvant/induction)
Cannot have received: immunotherapy
prior chemo- or immunotherapy (neoadjuvant/induction)
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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