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OncoMatch/Clinical Trials/NCT06013618

Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

Is NCT06013618 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments for neuroblastoma.

Phase 2RecruitingSun Yat-Sen University Cancer CenterNCT06013618Data as of May 2026

Treatment: Naxitamab monotherapy · GM-CSF · Irinotecan · Temozolomide · Naxitamab in combination therapy · GM-CSF with combination regimen · SintilimabThis is an prospective study to evaluate the safety and efficacy of naxitamab monotherapy or combined with chemotherapy or combined with chemotherapy and checkpoint inhibitor in the treatment of pediatric high-risk and refractory/relapsed neuroblastoma in Sun Yat-sen University Cancer Center.

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Extracted eligibility criteria

Cancer type

Neuroblastoma

Prior therapy

Cannot have received: investigational drug

has received another investigational drug within the 4 weeks prior to commencing treatment with naxitamab

Lab requirements

Cardiac function

Left ventricular ejection fraction of <50% by echocardiography OR other clinically relevant cardiac disorders at the discretion of the investigator

Left ventricular ejection fraction of <50% by echocardiography OR other clinically relevant cardiac disorders at the discretion of the investigator

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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