OncoMatch/Clinical Trials/NCT06010329
A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC
Is NCT06010329 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Sutetinib Maleate Capsule for non-small cell lung cancer.
Treatment: Sutetinib Maleate Capsule — The main objective of the study will be to evaluate the efficacy of sutetinib maleate capsules in participants with locally advanced or metastatic non-small cell lung cancer NSCLC (uncommon EGFR mutations only).
Check if I qualifyExtracted eligibility criteria
Cancer type
Non-Small Cell Lung Carcinoma
Biomarker criteria
Required: EGFR uncommon mutation
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: EGFR tyrosine kinase inhibitor
Exception: Cohort 1: ever used EGFR TKI; Cohort 2: any second generation EGFR TKI
Participant ever used the epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR TKI) for anti-tumor therapy prior to enrollment (Cohort 1), or second generation EGFR TKI (Cohort 2)
Cannot have received: systemic anti-tumor therapy
Any systemic anti-tumor therapy such as chemotherapy and radiation therapy (including curative radiotherapy or spinal radiotherapy portion >30%) used within 3 weeks prior to enrollment; immunotherapy within 4 weeks; any palliative radiotherapy for non-target lesions used to relieve symptoms and traditional Chinese medicines indicated for the tumor within 2 weeks prior to enrollment; Cohort 2: any EGFR TKIs within 5 half-lives.
Lab requirements
Blood counts
adequate bone marrow reserve
Kidney function
adequate renal function
Liver function
adequate hepatic function
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Oncology Physicians Network Healthcare · Glendale, California
- University of California San Diego Moores Cancer Center · La Jolla, California
- Moffitt Cancer Center · Tampa, Florida
- University Cancer & Blood Center (UCBC) - Athens · Athens, Georgia
- Mission Cancer + Blood - Mission Cancer Foundation · Des Moines, Iowa
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify