OncoMatch

OncoMatch/Clinical Trials/NCT05999994

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Is NCT05999994 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments for neoplasms.

Phase 2RecruitingEli Lilly and CompanyNCT05999994Data as of Jun 2026Location: International · 10 countries

Treatment: Ramucirumab · Cyclophosphamide · Vinorelbine · Gemcitabine · Docetaxel · Abemaciclib · Irinotecan · TemozolomideThe main purpose of the master is to help the research sites and sponsor carry out several clinical trials more efficiently by providing a common research protocol. Individual clinical trials under this master protocol define drug/disease-specific research goals and activities to test them. New studies will be added as new drugs emerge against different cancers. Participation in the trial will depend on how long the benefit lasts.

Check if I qualify

Extracted eligibility criteria

Treatments studied

Targeted therapy

RamucirumabAbemaciclib

Chemotherapy

CyclophosphamideVinorelbineGemcitabineDocetaxelIrinotecanTemozolomide

Demographics

Ages 1–39

Lab requirements

Blood counts

adequate hematologic function

Kidney function

adequate organ function

Liver function

adequate organ function

adequate hematologic and organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Childrens Hospital of Alabama · Birmingham, Alabama
  • Phoenix Children's Hospital · Phoenix, Arizona
  • Phoenix Children's Hospital · Phoenix, Arizona
  • Childrens Hospital of Los Angeles · Los Angeles, California
  • UCLA Medical Center · Los Angeles, California

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05999994 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 39 years or younger and at least 1 years old.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify