OncoMatch/Clinical Trials/NCT05989724
A First-in-Human Study of SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors
Is NCT05989724 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies SON-DP for solid tumor.
Treatment: SON-DP — This proposed Phase I clinical trial of SON-DP is an FIH, open-label, Phase Ia/Ib dose escalation and expansion study to evaluate the safety, tolerability, PK, and PD of SON-DP in participants with relapsed/refractory/intolerant to standard of care therapies, for advanced/ metastatic solid tumors.
Check if I qualifyExtracted eligibility criteria
Cancer type
Tumor Agnostic
Breast Carcinoma
Pancreatic Cancer
Ovarian Cancer
Colorectal Cancer
Disease stage
Metastatic disease required
relapsed/refractory intolerant to standard of care therapies for advanced/metastatic solid tumors
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: standard of care therapies — advanced/metastatic
relapsed/refractory intolerant to standard of care therapies for advanced/metastatic solid tumors
Cannot have received: investigational therapy
Participation in investigational study within 2 weeks or 5 half-lives, whichever is shorter of the first dose of study treatment.
Cannot have received: anticancer therapy
Anticancer therapy within 5 half-lives or 2 weeks (whichever is shorter) prior to study entry.
Lab requirements
Blood counts
adequate hematological function
Kidney function
adequate renal function
Liver function
adequate hepatic function
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Banner MD Anderson Cancer Center (BMDACC) · Gilbert, Arizona
- Henry Ford Health System · Detroit, Michigan
- Carolina BioOncology Institute · Huntersville, North Carolina
- Stephenson Cancer Center, University of Oklahoma · Oklahoma City, Oklahoma
- MD Anderson Cancer Center · Houston, Texas
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
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