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OncoMatch/Clinical Trials/NCT05986318

Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease

Is NCT05986318 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Dexamethasone Oral for lung cancer.

Phase 2RecruitingDavid PalmaNCT05986318Data as of May 2026

Treatment: Dexamethasone OralIn this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized using a 2 x 2 factorial design to oral N-acetylcysteine (NAC) versus placebo, and also to short course corticosteroids versus placebo.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Cannot have received: lung radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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