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OncoMatch/Clinical Trials/NCT05977998

A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology

Is NCT05977998 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including Paclitaxel and Dexamethasone for gastric adenocarcinoma.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT05977998Data as of Jun 2026

Treatment: Paclitaxel · Dexamethasone · Diphenhydramine · FamotidineTo learn about the effects of paclitaxel and gastrectomy (surgery to remove all or part of the stomach) on improving outcomes in patients with gastric cancer.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Paclitaxel

Other

DexamethasoneDiphenhydramineFamotidine

Cancer type

Gastric Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: systemic cytotoxic chemotherapy — preoperative

Completion of preoperative systemic cytotoxic chemotherapy

Lab requirements

Blood counts

Leukocytes 3,000/uL; Absolute neutrophil count 1,500/uL; Platelets 6,000/uL

Kidney function

Serum creatinine 1.6 mg/dL

Adequate renal, and bone marrow function: Leukocytes 3,000/uL; Absolute neutrophil count 1,500/uL; Platelets 6,000/uL; Serum creatinine 1.6 mg/dL

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05977998 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received systemic cytotoxic chemotherapy.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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