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OncoMatch/Clinical Trials/NCT05974449

Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients

Is NCT05974449 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Vaginal Lactobacillus capsules for breast cancer female.

Phase 2RecruitingThe First Affiliated Hospital with Nanjing Medical UniversityNCT05974449Data as of Jun 2026Location: China

Treatment: Vaginal Lactobacillus capsulesThis study is a prospective, randomized controlled, phase II clinical study with a planned enrolment of 60 patients. The study focuses on the efficacy and safety of Lactobacillus vaginalis capsules for the prevention and/or treatment of vulvovaginal symptoms in young breast cancer patients receiving ovarian protection during chemotherapy, in order to improve compliance and quality of life in breast cancer patients.

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Extracted eligibility criteria

Treatments studied

Other

Vaginal Lactobacillus capsules

Cancer type

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 45
Female only

Lab requirements

Kidney function

serum creatinine < 1.5x uln

Liver function

ast and alt < 1.5x uln, alkaline phosphatase < 2.5x uln, total bilirubin < 1.5x uln

Cardiac function

lvef >= 50% on cardiac ultrasound

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Frequently asked questions

Is NCT05974449 currently recruiting?

Yes, this trial is currently recruiting patients.

Is there an age limit?

Yes. Patients must be 45 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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