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OncoMatch/Clinical Trials/NCT05974449

Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients

Is NCT05974449 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Vaginal Lactobacillus capsules for breast cancer female.

Phase 2RecruitingThe First Affiliated Hospital with Nanjing Medical UniversityNCT05974449Data as of May 2026

Treatment: Vaginal Lactobacillus capsulesThis study is a prospective, randomized controlled, phase II clinical study with a planned enrolment of 60 patients. The study focuses on the efficacy and safety of Lactobacillus vaginalis capsules for the prevention and/or treatment of vulvovaginal symptoms in young breast cancer patients receiving ovarian protection during chemotherapy, in order to improve compliance and quality of life in breast cancer patients.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Lab requirements

Kidney function

serum creatinine < 1.5x uln

Liver function

ast and alt < 1.5x uln, alkaline phosphatase < 2.5x uln, total bilirubin < 1.5x uln

Cardiac function

lvef >= 50% on cardiac ultrasound

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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