OncoMatch/Clinical Trials/NCT05968768
To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)
Is NCT05968768 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Naxitamab for ewing sarcoma.
Treatment: Naxitamab — Prospective, interventional, open, randomized, national, multicenter, non-commercial trial
Check if I qualifyExtracted eligibility criteria
Cancer type
Sarcoma
Biomarker criteria
Required: GD2 positive expression (positive)
GD2 positive tumor assessed by IHC
Prior therapy
Must have received: systemic anticancer treatment
Documented disease progression (during or after completion of at least one line treatment) or any subsequent recurrence.
Cannot have received: anti-GD2 antibody
Previous treatment with an anti-GD2 antibody.
Lab requirements
Cardiac function
Significant cardiac conduction abnormalities, including known familial prolonged QT syndrome, or screening corrected QT interval (QTc) >480 msec. Symptoms of congestive heart failure or left ventricular ejection fraction <50%.
Significant cardiac conduction abnormalities, including known familial prolonged QT syndrome, or screening corrected QT interval (QTc) >480 msec. Symptoms of congestive heart failure or left ventricular ejection fraction <50%.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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