OncoMatch

OncoMatch/Clinical Trials/NCT05959694

A Clinical Trial on the Safety and Efficacy of TQB3909 Tablets in Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL) .

Is NCT05959694 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies TQB3909 tablet for chronic lymphocytic leukemia.

Phase 1/2RecruitingChia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT05959694Data as of Jun 2026Location: China

Treatment: TQB3909 tabletThis is a phase Ib/II clinical trial to evaluate the safety and efficacy of TQB3909 tablets in patients with recurrent or refractory CLL/SLL.

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Extracted eligibility criteria

Treatments studied

Other

TQB3909 tablet

Cancer type

Chronic Lymphocytic Leukemia

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Prior therapy

Cannot have received: allogeneic hematopoietic stem cell transplant

Previously received allogeneic hematopoietic stem cell transplantation

Cannot have received: autologous hematopoietic stem cell transplant

Exception: within 3 months before the first medication

Received autologous hematopoietic stem cell transplantation within 3 months before the first medication

Cannot have received: chemotherapy

Exception: within 4 weeks before the first medication

He has received chemotherapy and radiotherapy within 4 weeks before the first medication

Cannot have received: radiation therapy

Exception: within 4 weeks before the first medication

He has received chemotherapy and radiotherapy within 4 weeks before the first medication

Cannot have received: immune checkpoint inhibitor

Exception: within 12 weeks before the first medication

immune checkpoint inhibitor ... within 12 weeks before the first medication

Cannot have received: CAR-T cell therapy

Exception: within 12 weeks before the first medication

Chimeric Antigen Receptor T (CAR-T)-Cell Immunotherapy within 12 weeks before the first medication

Cannot have received: small molecule anti-tumor treatment

Exception: within 5 half-lives before the first medication

other small molecule anti-tumor treatments ... before the first medication are within 5 half-lives

Cannot have received: BCL2 inhibitor

previously received BCL-2 inhibitors

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05959694 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior allogeneic hematopoietic stem cell transplant, autologous hematopoietic stem cell transplant, chemotherapy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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