OncoMatch

OncoMatch/Clinical Trials/NCT05954897

Lenvatinib, Tislelizumab Combined With RALOX Regimen HAIC in Advanced Hepatocellular Carcinoma

Is NCT05954897 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Lenvatinib, Tislelizumab Combined with RALOX Regimen HAIC for hepatocellular carcinoma.

Phase 2RecruitingGuangdong Provincial People's HospitalNCT05954897Data as of Jun 2026Location: China

Treatment: Lenvatinib, Tislelizumab Combined with RALOX Regimen HAICTo evaluate the efficacy and safety of lenvatinib, tislelizumab combined with RALOX regimen HAIC in advanced hepatocellular carcinoma.

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Extracted eligibility criteria

Treatments studied

Other

Lenvatinib, Tislelizumab Combined with RALOX Regimen HAIC

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: liver transplantation

Previous liver transplantation

Lab requirements

Blood counts

Hb ≥ 90 g/dL; Neu ≥ 1.5 x 10^9/L; PLT ≥ 75 x 10^9/L; APTT ≤1.5 times the upper limit of normal

Kidney function

Cre ≤1.5 x upper limit of normal

Liver function

ALB ≥2.8 g/dL; TBIL ≤2 times the upper limit of normal; AST and ALT ≤ 3 times the upper limit of normal; Child-Pugh score ≤7

Adequate organ function, defined as: Hb ≥ 90 g/dL; Neu ≥ 1.5 x 10^9/L; PLT ≥ 75 x 10^9/L; ALB ≥2.8 g/dL; TBIL ≤2 times the upper limit of normal; AST and ALT ≤ 3 times the upper limit of normal; Cre ≤1.5 x upper limit of normal; APTT≤1.5 times the upper limit of normal. Child-Pugh score ≤7.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05954897 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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