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OncoMatch/Clinical Trials/NCT05941156

Clinical Study of Anti-CD56-CAR-T in the Treatment of Relapsed/Refractory NK/T Cell Lymphoma /NK Cell Leukemia

Is NCT05941156 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Anti-CD56 CAR T for extranodal nk t cell lymphoma.

Phase 2RecruitingThe Affiliated Hospital of Xuzhou Medical UniversityNCT05941156Data as of May 2026

Treatment: Anti-CD56 CAR TTo evaluate the safety and efficacy of anti-CD56-CAR T in the treatment of relapsed refractory NK/T cell lymphoma /NK cell leukemia

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: chemotherapy

relapse after chemotherapy

Must have received: hematopoietic stem cell transplantation

relapse after hematopoietic stem cell transplantation

Must have received: cellular immunotherapy

relapse or no remission after hematopoietic stem cell transplantation or cellular immunotherapy

Lab requirements

Kidney function

creatinine < 220 μmol/l

Liver function

alt/ast < 3 times the upper limit of normal (uln) and total bilirubin ≤34.2μmol/l

Cardiac function

left ventricular ejection fraction (lvef) ≥40%

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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