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OncoMatch/Clinical Trials/NCT05921253

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

Is NCT05921253 recruiting? Yes, currently enrolling (Jun 2026). This Early Phase 1 trial studies multiple treatments including PARASYM neuromodulation device and PARASYM neuromodulation device for breast cancer.

Early Phase 1RecruitingUniversity of OklahomaNCT05921253Data as of Jun 2026

Treatment: PARASYM neuromodulation device · PARASYM neuromodulation deviceThis study is to determine if low level vagus nerve stimulation will lead to improvement in heart function, heart rate variation, and in the levels of certain chemical markers of inflammation in study participants' blood.

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Extracted eligibility criteria

Treatments studied

Other

PARASYM neuromodulation devicePARASYM neuromodulation device

Cancer type

Breast Carcinoma

Non-Hodgkin Lymphoma

Hodgkin Lymphoma

Demographics

Ages ≤ 99

Prior therapy

Min 1 prior line

Must have received: anthracycline

have received anthracycline-based therapy for breast cancer or lymphoma within the last 30 days

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Stephenson Cancer Center · Oklahoma City, Oklahoma
  • Stephenson Cancer Center- Tulsa · Tulsa, Oklahoma

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05921253 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received anthracycline.

Is there an age limit?

Yes. Patients must be 99 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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