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OncoMatch/Clinical Trials/NCT05880667

Adaptive Radiation for Abdominopelvic Metastases

Is NCT05880667 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies non-drug interventions for neoplasm - soft tissue pelvis malignant secondary.

Phase 1RecruitingFox Chase Cancer CenterNCT05880667Data as of Jun 2026

Single arm Phase I trial of adaptive stereotactic body radiation (SBRT) for abdominopelvic metastases. Adaptive SBRT will allow for escalation of the prescription dose and target coverage while maintaining grade 3+ toxicity no greater than 10%. Subjects with metastatic cancer to the abdomen or pelvis requiring local control or palliation will be enrolled.

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Extracted eligibility criteria

Cancer type

Gastric Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: radiotherapy

Exception: Prior radiotherapy to non-target sites is allowed.

Subjects must not have had prior radiotherapy to any target metastatic lesion. Prior radiotherapy to non-target sites is allowed.

Lab requirements

Blood counts

absolute neutrophil count > 1,500/mcl; platelets > 100,000/mcl

Kidney function

creatinine < 1.5x uln or creatinine clearance ≥ 50 ml/min/1.73 m2 for subjects with creatinine levels above institutional normal

Liver function

total bilirubin < 2 mg/dl; ast/alt (sgot/sgpt) < 5x uln

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Fox Chase Cancer Center · Philadelphia, Pennsylvania

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05880667 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior radiotherapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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