OncoMatch

OncoMatch/Clinical Trials/NCT05879055

A Study of PM8002 in Combination With Chemotherapy in Patients With NEN

Is NCT05879055 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including PM8002 and FOLFIRI for neuroendocrine neoplasm.

Phase 2RecruitingBiotheus Inc.NCT05879055Data as of Jun 2026Location: China

Treatment: PM8002 · FOLFIRIPM8002 is a bispecific antibody targeting PD-L1 and VEGF. This study will evaluate the efficacy and safety of PM8002 in combination with FOLFIRI as second line treatment for neuroendocrine neoplasm (NEC and Ki-67≥55% G3 NET).

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Extracted eligibility criteria

Treatments studied

Other

PM8002FOLFIRI

Cancer type

Neuroendocrine Tumor

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 1 prior line

Must have received: platinum-based chemotherapy — first-line

Lab requirements

Blood counts

Adequate organ function

Kidney function

Adequate organ function

Liver function

Adequate organ function

Adequate organ function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05879055 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received platinum-based chemotherapy.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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