OncoMatch/Clinical Trials/NCT05871099
Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not
Is NCT05871099 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for gastric cancer.
The goal of this clinical trial is to learn about Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Gastric Cancer after Laparoscopic Gastrectomy with D2 Lymphadenectomy. The main question it aims to answer is: whether HIPEC can effectively improving the 5-year overall survival rate and decrease the peritoneal metastases rate of patients with advanced gastric cancer underwent Laparoscopic Gastrectomy with D2 Lymphadenectomy. Participants will be divided into two groups, Experimental group received laparoscopic (robotic) D2 surgery plus HIPEC2 times plus systemic chemotherapy 6\~8 cycles; and Control group received laparoscopic (robotic) D2 surgery plus systemic chemotherapy 6\~8 cycles.
Check if I qualifyExtracted eligibility criteria
Cancer type
Gastric Cancer
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Lab requirements
Blood counts
white blood cell count ≥3.5×10^9/L, neutrophil ≥1.5×10^9/L, platelet count ≥100×10^9/L, hemoglobin ≥90g/L
Kidney function
serum creatinine ≤1.5×ULN
Liver function
ALT≤2.5× upper limit of normal value (ULN), AST≤2.5×ULN, serum total bilirubin ≤1.5×ULN
The bone marrow reserve function was good, and the blood routine met the following conditions: white blood cell count ≥3.5×10^9/L, neutrophil ≥1.5×10^9/L, platelet count ≥100×10^9/L, hemoglobin ≥90g/L; Organ function was good, and biochemical examination met the following conditions: ALT≤2.5× upper limit of normal value (ULN), AST≤2.5×ULN, serum total bilirubin ≤1.5×ULN, serum creatinine ≤1.5×ULN
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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