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OncoMatch/Clinical Trials/NCT05849207

Post-Transplant Cyclophosphamide in Patients Aged >/= 65 Years Undergoing Haploidentical Transplant

Is NCT05849207 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies Cyclophosphamide for hematologic malignancies.

Phase 1RecruitingRonald PaquetteNCT05849207Data as of Jun 2026

Treatment: CyclophosphamideThe purpose of this phase 1 study is to determine the optimal dose of the immune suppressive drug, cyclophosphamide, following standard allogeneic stem cell transplant in patients aged \>/= 65 years with hematologic malignancies.

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Extracted eligibility criteria

Treatments studied

Chemotherapy

Cyclophosphamide

Cancer type

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Multiple Myeloma

Myelodysplastic Syndrome

Chronic Lymphocytic Leukemia

Demographics

Ages ≥ 65

Prior therapy

Cannot have received: stem cell transplant

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Cedars-Sinai Medical Center · Los Angeles, California

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05849207 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior stem cell transplant disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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