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OncoMatch/Clinical Trials/NCT05838729

Study of RiMO-301 and Radiotherapy With PD-1 Inhibitor for the Treatment of Head-Neck Cancer

Is NCT05838729 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies RiMO-301 for head neck cancer.

Phase 1/2RecruitingCoordination Pharmaceuticals, Inc.NCT05838729Data as of May 2026

Treatment: RiMO-301This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with hypofractionated radiation and a PD-1 Inhibitor in patients with unresectable, recurrent or metastatic head-neck cancer.

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Extracted eligibility criteria

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: anti-neoplastic agent or immunotherapy other than PD-1 inhibitors (pembrolizumab or nivolumab)

Has received any approved or investigational anti-neoplastic agent or immunotherapy other than PD-1 inhibitors (pembrolizumab or nivolumab) within 4 weeks prior to RiMO-301 injection

Lab requirements

Blood counts

adequate bone marrow reserve

Liver function

adequate liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Illinois at Chicago · Chicago, Illinois

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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