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OncoMatch/Clinical Trials/NCT05806580

Secondary Infusion of Relma-cel Injection for Relapsed or Refractory B-cell Lymphoma

Is NCT05806580 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies Relma-cel for relapsed or refractory b-cell lymphoma.

Phase 4RecruitingRuijin HospitalNCT05806580Data as of May 2026

Treatment: Relma-celTo observe the efficacy and safety of a second infusion of relma-cel injection in patients with relapsed or refractory B-cell lymphoma.

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Extracted eligibility criteria

Cancer type

Non-Hodgkin Lymphoma

Biomarker criteria

Required: CD19 positive

Prior therapy

Min 1 prior line

Must have received: CAR-T cell therapy (Relma-cel) — initial treatment

have completed initial treatment with Relma-cel

Must have received: disease assessment — post-initial Relma-cel treatment

must have undergone at least one disease assessment post-initial Relma-cel treatment

Must have received: lymphodepleting chemotherapy (fludarabine, cyclophosphamide)

Toxicity related to lymphodepleting chemotherapy (fludarabine and cyclophosphamide), except for hair loss, must have resolved to ≤ Grade 1 or returned to baseline levels before retreatment.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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