OncoMatch/Clinical Trials/NCT05804916
Optical Surface Monitoring Technology-Guided Large-Segment Radiotherapy for Breast Cancer
Is NCT05804916 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies Surface Guided Radiation Therapy (SGRT) for breast cancer.
Treatment: Surface Guided Radiation Therapy (SGRT) — This study is a single-center,blinded, efficacious, phase III randomized clinical trial initiated by investigators. The primary objective is to investigate the use of Surface Guided Radiation Therapy (SGRT) in combination with Deep Inspiration Breath Hold (DIBH) technique for left breast cancer treatment, compared to traditional laser alignment with free breathing treatment. This approach offers superior positioning accuracy and improved heart protection without any increase in radiation or adverse reactions.
Check if I qualifyExtracted eligibility criteria
Cancer type
Breast Carcinoma
Prior therapy
Must have received: surgery
Patients who have undergone breast-conserving surgery or modified radical mastectomy
Cannot have received: neoadjuvant chemotherapy
Patients who have not received neoadjuvant chemotherapy
Cannot have received: breast reconstruction surgery
Patients who have not received...breast reconstruction surgery
Cannot have received: mediastinal radiotherapy
Have received mediastinal radiotherapy in the past
Cannot have received: abdominal or pelvic radiotherapy
Previous history of abdominal or pelvic radiotherapy
Lab requirements
Cardiac function
No active heart disease, myocardial infarction, congestive heart failure or other cardiac diseases at baseline; Serious cardiac insufficiency; Myocardial infarction or uncorrected unstable arrhythmia or uncorrected unstable angina pectoris occurred in the last 3 months; Pericardial disease
No active heart disease, myocardial infarction, congestive heart failure or other cardiac diseases at baseline; Serious cardiac insufficiency; Myocardial infarction or uncorrected unstable arrhythmia or uncorrected unstable angina pectoris occurred in the last 3 months; Pericardial disease
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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