OncoMatch/Clinical Trials/NCT05800587
Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
Is NCT05800587 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments for lung cancer.
Treatment: Carboplatin · Pemetrexed · Paclitaxel · Nab paclitaxel · Docetaxel · Gemcitabine · Etoposide · Irinotecan · Topotecan · Lurbinectedin — This is an open-label, non-randomized, single-center, phase II study to evaluate the efficacy, toxicity and, tolerability of pre-specified dose attenuated chemotherapy regimens in lung cancer patients with comorbidities.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Chemotherapy
Cancer type
Non-Small Cell Lung Carcinoma
Small Cell Lung Cancer
Disease stage
Required: Stage IV, III (AJCC version 8)
stage IV (AJCC version 8) lung cancer (small cell or non-small cell). Patients with stage III disease who are not felt to be candidates for definitive therapy are also eligible.
Performance status
ECOG 0–3(Limited self-care)
Prior therapy
Cannot have received: targeted therapy (TKI, sotorasib)
Exception: if not combined with a cytotoxic agent
Patients receiving only a targeted agent (e.g. TKI, sotorasib etc.) or immunotherapy without a cytotoxic agent
Cannot have received: immunotherapy
Exception: if not combined with a cytotoxic agent
Patients receiving only a targeted agent (e.g. TKI, sotorasib etc.) or immunotherapy without a cytotoxic agent
Cannot have received: investigational agent
Patients currently receiving investigational agents for cancer
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Fox Chase Cancer Center · Philadelphia, Pennsylvania
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT05800587 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior targeted therapy, immunotherapy, investigational agent disqualifies patients from enrollment.
What disease stage is eligible?
Stage IV or III is required.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualify