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OncoMatch/Clinical Trials/NCT05799248

Role of rhPSMA-7.3 PET/CT Imaging in Men With High-Risk Prostate Cancer Following Conventional Imaging and Associated Changes in Medical Management

Is NCT05799248 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies rhPSMA-7.3 (18F) for prostate cancer.

Phase 3RecruitingMidLantic UrologyNCT05799248Data as of May 2026

Treatment: rhPSMA-7.3 (18F)Study Title: Role of rhPSMA-7.3 PET/CT imaging in men with High-Risk prostate cancer following conventional imaging and associated changes in medical management Protocol number: BED-IIT-437 Phase: 3b Sponsor: MidLantic Urology Funding Organization: Blue Earth Diagnostics Ltd Study Design: This is a Phase 3b, multi-center, single-arm, diagnostic imaging study designed to detect metastatic lesions in men diagnosed with high-risk prostate cancer.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Grade: primary Gleason grade 4any Gleason grade 5 (Gleason)

High-risk patients will be defined as having any of the following criteria: primary Gleason grade 4, or any Gleason grade 5, PSA ≥20, or clinical stage T3a (per NCCN Guidelines Version 2.2019; PROS-2).

Prior therapy

Cannot have received: androgen deprivation therapy (surgical orchidectomy, LHRH agonist, LHRH antagonist, first generation anti-androgen, second generation anti-androgen)

Patients currently receiving, or with a prior history of, androgen deprivation therapy (ADT; defined as surgical orchidectomy; luteinizing hormone-releasing hormone [LHRH] agonist alone [continuous or intermittent]; LHRH antagonist alone [continuous or intermittent]; administration or use of a first generation or second generation anti-androgen alone or in combination with an LHRH agonist/antagonist).

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MidLantic Urology · Bala-Cynwyd, Pennsylvania

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